Our Therapeutics Pipeline
Current research works
Our current research works
In Silico – In Vitro – In Vivo
Since the beginning of 2022 CancerAppy has focused on the discovery and development of new therapeutic targets in cancer.
All this thanks to the development of our AI platform in collaboration with our scientific advisors.
CA01
Identified a Therapeutic Target in Breast Cancer Triple Negative with clear oncogenic role.
CA02/03
Identified CA02- CA03, two membrane proteins that are upregulated in NSCLC with K-RAS G12C mutation and has patented their use as targets to vectorize compounds against these tumors, or as surrogates for immune activation, to select patients o explore combinations with new immune therapies.
CA04
Developing CA04 an Antibody and Antibody Drug Conjugates against Therapeutic Target in Pancreatic Cancer, with clear oncogenic role.
CA05
We have identified insilico, several compounds as inhibitors of CA05, which is a protein kinase overexpressed in various types of tumors with a clear oncogenic role and no type-specific inhibitor, and we have started in vitro trials to select a lead.
CA07
Thanks to the funding received from the CPP22 program we are developing a PROTACs for a target in TNBC.
Current Research Projects
Pipeline
In Silico Discovery
Pre-Clinical Phase – Non GLP
Lead to Candidate
Preclinical Phase – Pre IND
IND-enabling Studies
- CA01 – Solid Tumors
- CA02-03 Solid Tumors
- CA04 Solid Tumors Ab
- CA05 Solid Tumors SM
- CA07 Solid Tumors – PROTAC
The rapid growth of the internal pipeline demonstrates the great drug discovery capabilities driven by the use of our AI platform.
Likewise, our partners and collaborators take advantage of our technology and high scientific knowledge to increase and accelerate their initiatives for the discovery and development of new drugs against cancer.
Target Identification
We combine our expertise in biology and AI to identify new therapeutic targets.
Lead Identification
We combine our expertise in chemistry and AI to identify new chemical compounds with the potential to be novel inhibitors of therapeutic targets.
Mechanism of action
We can find the possible mechanism of action of a compound.
The programs below are progressing into the early preclinical stage.
However they are programs that are available under CDA.
Contact us for partnership opportunities.
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